Diseases and conditions
Infectious · Cat

Feline viral disease screening

FeLV and FIV: understanding the tests and what the results truly mean for your cat

Just received a positive result?

A first positive test is not a verdict. FeLV and FIV often require confirmation. Read this page, then call your clinic: that is the next step, not the last.

FeLV and FIV: two viruses, two very different realities

They are often tested together - yet these two retroviruses have almost nothing in common, neither in how they spread nor in what they mean for your cat.

FeLV
Feline Leukemia Virus
Transmission:Saliva, milk, urine - close, prolonged contact
Risk:Kittens and young cats: high risk
Impact:Immunosuppression, anemia, tumors
FeLV is fragile outside a host: it survives only a few hours in the environment. Transmission requires real and sustained contact - mutual grooming, shared bowls, close cohabitation.
FIV
Feline Immunodeficiency Virus
Transmission:Mainly deep bite wounds
Risk:Unneutered outdoor males: highest risk group
Impact:Slow progressive immunosuppression
FIV does not spread easily. Simple cohabitation, sharing bowls or litter boxes is generally not enough. The main risk comes from deep bite wounds during territorial fights.
How they differ in practice
FeatureFeLVFIV
TransmissionGentle contact (grooming, bowls)Deep bite wounds mainly
Most affected ageKittens, young adultsAdults (especially outdoor males)
Survival untreated< 3 years average if progressiveOften normal with monitoring
Vaccine availableYes (recommended)Yes (with limitations)
Transmissible to humansNoNo

When and why to test your cat?

Viral screening is part of the standard workup in several situations. Knowing your cat's status protects them - and any other cats in your household.

New cat or kitten

Any adopted cat should be tested before joining a household with other cats, even if they appear healthy. A negative result obtained too soon after exposure can give false reassurance.

Wait 60 days after the last potential exposure before relying on the result.

Sick cat with no clear cause

Unexplained weight loss, repeated infections, anemia, chronic digestive issues: these signs warrant viral screening even in an indoor cat.

Outdoor or stray cat

Cats with outdoor access, especially unneutered males, have a higher FIV risk. Annual screening is recommended.

Before vaccination

Knowing FeLV/FIV status before vaccinating allows the protocol to be adjusted and avoids unknowingly vaccinating an already-positive cat.

Before adoption or rehoming

Shelters test routinely. If adopting from a private individual, ask that the cat be tested, or have it done upon arrival.

Understanding your test result

The SNAP test (rapid blood or serum test) is the initial screening tool. It detects antibodies (FIV) or antigens (FeLV). A first result - positive or negative - is never definitive in certain contexts.

FeLV Negative + FIV Negative

Reassuring, but not absolute

  • Your cat was probably not infected at the time of testing.
  • If exposure was recent (under 60 days), retest later.
  • If the cat goes outdoors: annual screening recommended.
FeLV Positive

Confirm before concluding

  • A single positive test is not enough for a definitive diagnosis.
  • A confirmatory test (IFA or PCR) is recommended, especially if the cat appears healthy.
  • Three possible outcomes: see the dedicated section below.
FIV Positive

Beware of false positives

  • The SNAP FIV test detects antibodies, not the virus itself.
  • Kittens under 6 months can be false positives (maternal antibodies).
  • A confirmatory PCR test is recommended when in doubt.
FeLV Positive + FIV Positive

Dual infection: close monitoring needed

  • Possible but uncommon.
  • Confirmation of both viruses recommended.
  • Increased veterinary monitoring required.
Why a confirmatory test?

Rapid tests are excellent for screening, but they have a margin of error. A positive result in a cat without symptoms or risk factors always warrants confirmation. Confirmation is not a challenge to the test - it is good medical practice.

The 3 possible outcomes of FeLV infection

Contrary to common belief, a cat exposed to FeLV does not automatically become a permanent carrier. The outcome depends on several factors, including age at exposure and viral load.

~30%
Abortive outcome
(complete elimination)
The immune system eliminates the virus before it takes hold. The antigen disappears and the cat fully recovers. This happens mainly in healthy adults.
The cat gains partial protection against re-exposure.
~30%
Regressive outcome
(latent virus)
The virus is contained but not eliminated. It hides in the bone marrow in a dormant state. The cat tests antigen-negative on SNAP, but can reactivate the virus if immunocompromised.
These cats are generally not contagious. Annual follow-up is recommended.
~30%
Progressive outcome
(persistent infection)
The virus establishes permanently in the body. The cat is chronically infected and contagious. This is the group where serious complications (anemia, tumors, immunosuppression) occur.
With appropriate care, some cats live several quality years.
The critical window: kittens and immunocompromised cats have a much higher risk of a progressive outcome. Age at time of exposure is the single most important prognostic factor.

FIV and kittens: the maternal antibody issue

A positive FIV result in a kitten almost never means it is truly infected. This is one of the most common - and anxiety-inducing - sources of confusion in feline medicine.

What actually happens
0-6 weeks

The kitten receives the mother's antibodies via milk (or in utero). If the mother is FIV+, the kitten will carry her antibodies.

6-16 weeks

Maternal antibodies are still present in the blood. A SNAP test will be positive - but these are the mother's antibodies, not a sign of active infection.

6 months and older

Maternal antibodies have disappeared. If the test is still positive at this age, the kitten is likely truly infected.

Recommendation: do not draw definitive conclusions from a positive FIV test in a kitten under 6 months. Retest after 6 months, or request a PCR for confirmation.
What about the FIV+ mother?

A FIV-positive cat can give birth to healthy kittens. The virus does not spread easily from mother to kittens in utero or through milk (unlike FeLV). Neutering and indoor living considerably limit transmission risk.

Living with a FeLV+ or FIV+ cat

A positive diagnosis is not the end. Thousands of cats across Canada live happy years with one or the other of these viruses, with appropriate monitoring.

Indoor life required

A positive cat should not go outdoors unsupervised. This protects them from opportunistic infections and protects neighboring cats.

Cohabitation with other cats

FIV: possible if cats are non-aggressive. FeLV: real risk of transmission with close cohabitation. Your veterinarian will guide you based on your specific situation.

Veterinary check-up every 6 months

Blood work, weight, oral exam, signs of secondary infection. The goal is to catch complications early, not wait until they become serious.

Adapted vaccines

Core vaccines (calicivirus, panleukopenia, rhinotracheitis) remain important for an immunocompromised cat. Discuss the protocol with your veterinarian.

Quality of life first

Quality nutrition, environmental enrichment, minimal stress: these elements have a real impact on disease progression. A happy cat is a cat that fights better.

Do I need to separate my cats?

FIV: FIV: cohabitation is generally safe if cats are neutered and non-aggressive. The virus does not typically spread through shared bowls in most cases.
FeLV: FeLV: the risk is more real. If you have multiple cats, consult your veterinarian to assess the situation. Regular testing of other cats is recommended.

Home care

Daily priorities

  • High-quality diet (digestible protein, low carbohydrates)
  • Fresh water always available - fountain recommended
  • Clean litter box, scooped 1-2 times daily
  • Minimize stress: stable routine, multiple rest areas
  • Monitor appetite, weight, and stools

Warning signs to watch for

  • Loss of appetite lasting more than 24-48 hours
  • Sudden or unusual lethargy
  • Fever (very warm ears, shivering)
  • Difficulty breathing
  • Persistent diarrhea or vomiting
  • Pale gums

When to call the clinic

  • Any warning sign listed above
  • Progressive weight loss (even slow)
  • Unexplained behavior change
  • Before any new medication or supplement
  • When in doubt - better to call

Frequently asked questions

Can my FIV+ cat transmit the virus to my children or me?
No. FIV is strictly specific to felines. It cannot infect humans, dogs, rabbits, or other pets. You can handle and care for your cat without any risk to your own health.
My FeLV+ cat looks perfectly healthy. Is that possible?
Absolutely. The period between infection and first clinical signs can last months or even years in some cases. An asymptomatic FeLV+ cat is nonetheless contagious to other cats and should be monitored regularly.
Should a FeLV or FIV positive cat be euthanized?
No. A positive diagnosis does not justify euthanasia if the cat is not suffering. Many cats live years of good quality with these viruses. End-of-life decisions are based on actual suffering and quality of life, not a test result.
Do human antiviral medications (like HIV antiretrovirals) work in cats?
Some antiviral molecules have been studied in feline medicine with variable results. A specific antiviral approved for FIV exists in some countries (GS-441524). Talk to your veterinarian: therapeutic options are evolving rapidly.
Can I adopt another cat if I already have a FIV+ cat?
It depends on the cats' profiles. Since FIV spreads mainly through bites, two calm neutered cats can often cohabitate without major risk. A slow, supervised introduction and regular testing of the newcomer are essential. Consult your veterinarian before acting.
Is the FIV vaccine reliable? Is it worth it?
The available FIV vaccine offers partial protection. Its use also complicates interpretation of future tests (vaccinated cats may test false positive). It is recommended primarily for high-risk cats (outdoor access, unneutered males, frequent fight environments). Discuss the risk-benefit with your veterinarian.
My cat tested negative but lived with a FeLV+ cat. What should I do?
A negative test within 60 days of exposure may be false. Retesting at 60 days and 6 months after the last exposure is recommended. In the meantime, limit contact with other uninfected cats.

Let's talk about your cat's result

A positive test deserves a consultation, not an online anxiety spiral. Our team can explain the next steps, interpret the results, and build a monitoring plan suited to your cat.

This page is an educational resource. It does not replace a veterinary consultation. If your cat has been tested, please book an appointment to discuss the results with your veterinarian.